Lub Ntiaj Teb Hallucinogenic Ntawm Tryptamines: Kev Ntsuam Xyuas Hloov Kho
Lub Ntiaj Teb Hallucinogenic Ntawm Tryptamines: Kev Ntsuam Xyuas Hloov Kho
AbstractIn thaj tsam ntawm cov tshuaj psychotropic, tryptamines paub tias yog ib chav dav dav ntawm classical lossis serotonergic hallucinogens. Cov tshuaj no muaj peev xwm tsim tau qhov kev hloov pauv loj hauv kev nkag siab, lub siab xav, thiab kev xav hauv tib neeg thiab ua raws li agonists ntawm 5-HT2A receptor.
Cov npe nrov tryptamines xws li psilocybin muaj nyob rau hauv Aztec dawb ceev nceb thiab N, N-dimethyltryptamine (DMT), tam sim no nyob rau hauv South American psychoactive dej haus ayahuasca, tau txwv tsis pub siv txij thaum ancient sij hawm nyob rau hauv sociocultural thiab ritual ntsiab lus.
Txawm li cas los xij, nrog kev tshawb pom ntawm cov khoom muaj txiaj ntsig ntawm lysergic acid diethylamide (LSD) hauv nruab nrab xyoo 1900s, tryptamines tau pib siv ua si ntawm cov tub ntxhais hluas.
Tsis ntev los no, tshiab synthetically tsim tryptamine hallucinogens, xws li alpha-methyltryptamine (AMT), 5-methoxy-N, N-dimethyltryptamine (5-MeO-DMT) thiab 5-methoxy-N, N-diisopropyltryptamine (5-MeO-DIPT. ), tau tshwm sim hauv kev ua lag luam tshuaj lom neeg, uas tau lees paub tias yog cov tshuaj tsim qauv tshiab los hloov LSD ('kev cai lij choj' lwm txoj hauv kev rau LSD).
Tryptamine derivatives tau dav siv hauv Is Taws Nem los ntawm cov tuam txhab muag lawv li 'kev tshawb fawb tshuaj, tab sis kuj tseem tuaj yeem muag hauv 'headshops' thiab cov neeg muag hauv txoj kev. Cov ntawv ceeb toom ntawm kev qaug cawv thiab kev tuag cuam tshuam nrog kev siv cov tryptamines tshiab tau piav qhia nyob rau ob peb xyoos dhau los, nce kev txhawj xeeb thoob ntiaj teb txog tryptamines.
Txawm li cas los xij, qhov tsis muaj cov ntaub ntawv hais txog cov tshuaj pharmacological thiab toxicological ntawm cov tryptamine hallucinogens tshiab cuam tshuam qhov kev ntsuam xyuas ntawm lawv qhov muaj peev xwm tsim kev puas tsuaj rau pej xeem kev noj qab haus huv.
Qhov kev tshuaj xyuas no muab cov kev hloov kho tshiab ntawm tryptamine hallucinogens, hais txog lawv keeb kwm keeb kwm, kev nthuav dav, cov qauv ntawm kev siv thiab kev cai lij choj, chemistry, toxicokinetics, toxicodynamics, thiab lawv cov teebmeem physiological thiab toxicological rau tsiaj thiab tib neeg.
Lub Ntiaj Teb Hallucinogenic Ntawm Tryptamines: Kev Ntsuam Xyuas Hloov Kho
